src: i.ytimg.com
Mast cell stabilizers are cromone medications used to prevent or control certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate.
As inhalers they are used to treat asthma, as nasal sprays to treat hay fever (allergic rhinitis) and as eye drops for allergic conjunctivitis. Finally, in oral form, they are used to treat the rare condition of mastocytosis.
Video Mast cell stabilizer
Examples
Mast cell stabilizer medications include:
- ?2-adrenergic agonists
- Cromoglicic acid
- Ketotifen
- Methylxanthines
- Olopatadine
- Mepolizumab
- Omalizumab
- Pemirolast
- Quercetin
- Nedocromil
- Azelastine
Maps Mast cell stabilizer
References
Source of the article : Wikipedia
0 Comments